Direct switch from TNFi to tofacitinib shows ‘acceptable’ safety in psoriatic arthritis

For patients with psoriatic arthritis, switching directly from adalimumab to tofacitinib with no washout period presents no increased safety risks, according to data published in Arthritis Research & Therapy.
“There are no available data from randomized controlled trials in PsA assessing clinical outcomes in patients who have directly switched from [TNF inhibitors] to tofacitinib, and whether they maintain or achieve disease control with an acceptable safety profile,” Dafna D. Gladman, MD, of the department of medicine at the University of Toronto, and colleagues wrote.
“Given

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Genetics, brain development, and mental health shape teen eating

Investigating the interplay of genetics, brain maturation, and mental health, this study reveals insights into adolescent eating behaviors and obesity risk.

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Genetics, brain development, and mental health shape teen eating

Investigating the interplay of genetics, brain maturation, and mental health, this study reveals insights into adolescent eating behaviors and obesity risk.

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Most Kids With COVID-Linked MIS-C Recover by 6 Months

Midterm data from the MUSIC study show excellent cardiovascular and noncardiovascular outcomes. Pediatricians can have “a moment of collective exhale.”

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Valaciclovir May Prevent Herpes Zoster in Lupus Treatment

Prophylactic valaciclovir was effective and prevented herpes zoster in patients with systemic lupus erythematosus receiving anifrolumab, a treatment otherwise linked to an increased risk for herpes.

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